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Amphetamine is thought to inhibit monoamine oxidase, whereas the ability of amphetamine and its metabolites to inhibit many P450 isozymes and other enzymes hasn't been adequately elucidated. In vitro experiments with human microsomes indicate minimal inhibition of CYP2D6 by amphetamine and slight inhibition of CYP1A2, 2D6, and 3A4 by a number of me

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